서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2017년 11월 09일 목요일 오전 11시

연사: 고광표 (서울대학교 보건대학원)

장소: 서울대학교 25동 411호

Title : Genomics Approach for Microbiome Therapeutics

Abstract : There were dramatically increased interests on human microbiome research worldwide. While human ecosystems is maintained through mutualistic relationship between host and microbiota, human microbiota is certainly to play a crucial role in development and function of the immune system. Recent advances in metagenomics and metabolomics techniques provide the enormous amount of evidences of specific microorganisms and their functions for controlling the host immune and metabolic status. Particularly, a number of recent studies indicated that gut microbiota and their metabolites play an important role in educating and modulating the host immune system. Currently, a number of research groups are vigorously investigating to identify the etiological agents of microorganisms and their metabolites for various diseases and to develop the novel drugs using these substances. This talk will help to understand the current status and predict the future application of microbiome therapeutics.

Education

Experience

Selected Publications

1. Si J, You HJ, Sung J, and Ko G*. 2017. Prevotella as a hub for vaginal microbiota under the influence of host genetics and their association with obesity. Cell Host Microbe. 21(1):97-105.

2. Lim MY, You HJ, Yoon HS, Kwon B, Lee KY, Lee S, Song YM, Sung J, Ko G*. 2017. The effect of heritability and host genetics on the gut microbiota and metabolic syndrome. Gut, Apr 6, 2015-311326

3. Lee H and Ko G*, 2016, Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome, Sci. Rep. 16:6:25835

4. Lim MY, You HS, Rho M, Sung J, Lee K, Ko G*. 2016. Analysis of the association between host genetics, smoking, and sputum microbiota in healthy humans. Sci. Rep., 31:6:23745

5. Yassour M, Lim My, Yun HS, Tickie TL, Sung J, Song YM, Lee K, Franzosa EA, Morgan XC, Gevers D, Landers ES, Xavier RJ, Birren BW, Ko G, and Huttenhower G, 2016, Subclinical detection of gut microbial biomarkers of obesity and type 2 diabetes, Genome Med, 17(8):17

6. Si J, Lee S, Park JM, Sung J, and Ko G*. 2015. Genetic associations and shard environmental effects on the skin microbiome of Korean twins. BMC Genomics, 23:16:992.

7. Lee S, Cantarel B, Henrissat B, Gevers D, Birren BW, Huttenhower C, Ko G*. 2014. Gene-targeted metagenomic analysis of glucan-branching enzyme gene profiles among human and animal fecal microbiota. ISME J. 8:493-503.

8. Lim MY, Rho M, Song YM, Lee KY, Sung J, Ko G*. 2014. Stability of gut enterotypes in Korean monozygotic twins and their association with biomarkers and diet. Sci. Rep. 8:4:7328.

9. Lee H, Ko G*. 2014. Effect of metformin on metabolic improvement and gut microbiota. Appl Environ Microbiol. 80:5935-5943.

서울대학교 생물정보연구소·생물정보학 협동과정 공동주최