서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2017년 9월 28일 목요일 오전 11시

연사: 노미나 (한양대학교 컴퓨터소프트웨어학과)

장소: 서울대학교 25동 411호

Title: Mobile genetic elements in eukaryotic and prokaryotic genomes

Abstract: Mobile genetic elements (MGEs) constitute a significant portion of the eukaryotic and prokaryotic genomes, and play important roles as a driver of genomic instability and regulatory elements. As such, the identification of novel MGEs in individual genomes and the analysis of their dynamics are important for a better understanding of the genome instability as one of the factors responsible for diseases. Recent advances in sequencing technology have allowed us to investigate personal genomes to find structural variations, which have been studied extensively to identify the association with the physiology of diseases such as cancer. We have developed a new program to identify such novel MGEs by using sequencing reads of individual genomes, and to explore the breakpoints with the supporting reads and MGEs detected.

Education

Aug 2003–Nov 2009 Ph.D., Computer Science, Indiana University, Bloomington, IN

Sep 1999–Jan 2001 M.S., Computer Engineering, Boston University, Boston, MA Mar 1992–Feb 1998 B.S. and M.S., Computer Science, Ewha Womans University, Seoul, Korea

Experience

Sep 2017 – present Associate Professor, Division of Computer Science and Engineering, Hanyang University, Seoul, Korea

Sep 2013 – Aug 2017 Assistant Professor, Division of Computer Science and Engineering, Hanyang University, Seoul, Korea

Jul 2012 – Apr 2013 Assistant Professor, Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, NY

Oct 2009 – Jun 2012 Postdoctoral Associate, laboratories of Professors Yuzhen Ye and Haixu Tang, Indiana University, Bloomington, IN

Sep 2005 – Oct 2009 Research Assistant, laboratory of Professor Haixu Tang

Jan 2004 – Aug 2005 Associate Instructor, Department of Computer Science

Recent Publications

(1) K. Yihwan, I. Koh, M.Y. Lim, W. Chung, and M. Rho (2017) “Pan-genome analysis of Bacillus for microbiome profiling”, Scientific Reports :7(10984), DOI:10.1038/s41598-017-11385-9

(2) H. Cho, J. Choi, J. Seo, B.J. Kim, M. Rho∗,J. K. Han, and J. G. Kim∗ (2017) “Helicobacter pylori-derived extracellular vesicles increased in the gastric juices of gastric adenocarcinoma patients and induced inflammation mainly via specific targeting of gastric epithelial cells”, Experimental & Molecular Medicine :49, e330, DOI:10.1038/emm.2017.47

(3) H. J. Song, M. Rho, J. Lee, L. Graf, H. Qiu, D. Bhattacharya, and H. S. Yoon (2017) “A novice’s guide to analyzing NGS-derived organelle and metagenome data”, Algae :31(2), DOI:10.4490/algae.2016.31.6.5

(4) H. Lee, M. Lee, W. Ismail, M. Rho, G. Fox, S. Oh, and H. Tang (2016) “MGEScan:aGalaxy-based system for identifying retrotransposons in genomes”, Bioinformatics :32(16), DOI:10.1093/bioinformatics/btw157

(5) W. Magner, B. Weinstock-Guttman, M. Rho, D. Hojnacki, R. Ghazi, M. Ramanathan, and T. Tomasi (2016) “Dicer and microRNA expression in multiple sclerosis and response to interferon therapy”, J. of Neuroimmunology :292, DOI:10.1016/j.jneuroim.2016.01.009

(6) M. Lim, H. Yoon, M. Rho, J. Sung, Y. Song, K. Lee, and G. Ko (2016) “Analysis of the association between host genetics, smoking, and sputum microbiota in healthy humans”, Scientific Reports :6, DOI:10.1038/srep23745

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