서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2017년 5월 31일 수요일 오전 11시

연사: 남궁정현(SK 텔레콤)

장소: 서울대학교 25동 411호

TITLE: Clinical Applications of Cell-free DNA Analysis

ABSTRACT: In this talk, origin of cell-free DNA (cfDNA) of human and the features will be introduced at first. Two clinical applications of the cfDNA sequencing analysis, liquid biopsy for cancer patient and prenatal diagnosis, will be reviewed. Lastly, Novel analysis methods for a fetal monogenic disease risk will be briefly explained.

EDUCATION AND TRAINING

2009-2011 Post-doc Case Western Reserve University School of Medicine

Department of Epidemiology and Biostatistics

Training in Statistical Genetics (Robert C. Elston)

2003-2009 Ph.D. Seoul National University, Seoul, Korea

Interdisciplinary program in Bioinformatics

Department of Statistics (Taesung Park)

2001 Korea National institute of Health, Seoul, Korea

Training Courses in Bioinformatics

1994-1999 B.S. Korea University, Seoul, Korea

Major in Genetic Engineering

ATTENDED KEY PROJECTS

2012-2015 Pancreatic cancer biomarker project

- Plan and conduct multicenter clinical studies

- Conduct statistical analysis of clinical data

- Write manuscripts/patents

2013-2014 Prenatal diagnosis of a mendelian disease

- Develop analysis algorithm and software

- Write manuscripts/patents

2015-2016 Prenatal diagnosis of chromosomal aneuploidy

- Develop analysis software

- ISO/CE application

Selected Publications

1. Namkung J, Kwon W, Choi Y, Yi SG, Han S, Kang MJ, Kim SH, Park T, Jang JY. Molecular subtypes of pancreatic cancer based on miRNA expression profiles have independent prognostic value. J Gastro Hepatol 2015

2. Kwon MS, Kim Y, Lee S, Namkung J, Yun T, Yi SG, Han S, Kang M, Kim SW, Jang JY, Park T. Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer. BMC Genomics. 2015;16 Suppl 9:S4

3. Yoo SK, Lim BC, Byeun J, Hwang H, Kim KJ, Hwang YS, Lee JH, Park JS, Lee Y, Namkung J, Jungsun Park, Seungbok Lee, Jong-Yeon Shin, Jeong-Sun Seo, Jong-Il Kim. Noninvasive Prenatal Diagnosis of Duchenne Muscular Dystrophy: Comprehensive Genetic Diagnosis in Carrier, Proband, and Fetus. Clinical Chemistry 2015 Jun;61(6):829-37

4. Namkung JH, Lee JE, Kim E, Huh IS, Park T, Shin ES, Cho EY, Yang JM, Single nucleotide polymorphism in the FLT4 gene is associated with atopic dermatitis in Koreans. Cytokine 2013 Apr;62(1):110-4

5. Kotnis A, Namkung J, Kannan S, Jayakrupakar N, Park T, Sarin R, Mulherkar R. Multiple pathway-based genetic variations associated with tobacco related multiple primary neoplasms. PLoS ONE 01/2012; 7(1):e30013.

6. Shetty PB, Qin H, Namkung J, Elston RC, Zhu X. Estimating heritability using family and unrelated individuals data. BMC proceedings 11/2011; 5 Suppl 9:S88.

서울대학교 생물정보연구소

생물정보학 협동과정 공동주최