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Zoom link: http://snu-ac-kr.zoom.us/s/97407360145


Microbiome and Precision Medicine

Hansoo Park Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju, 61005, Korea


The gut microbiome of patients with disease is believed to influence the development of disease, as well as the efficacy of the drugs. Human Microbiome research was conducted to understand how microbial communities impact on human health. However, the genomic characteristics and detailed functions of effective bacterial strains have not been fully clarified. In this study, we utilized an integrated approach, involving metagenome, bacterial whole genome/transcriptome, mouse intestinal transcriptome, and mouse serum metabolome analysis, to decipher whether bacterial strain-specific differences influence the disease susceptibilities and efficacy of therapeutics in various diseases.