서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 특별 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2015년 9월 9일 수요일 오전 11시

연사: 김정수 (서울대학교 자연과학대학)

장소: 서울대학교 25동 411호

Title: A statistical analysis for Next-Generation Sequencing data with a small number of samples

Abstract:

In this talk, approaches to genomic and transcriptomic data with small sample sizes will be provided. Specifically, a new strategy called multiphasic analysis for familiar genomic data is suggested. Appling the strategy to a Mendelian disease, the strategy shows how it efficiently weed out a disease-causing variant from various candidates. For transcriptomic data, a method is proposed for differential expression analysis, which can be applicable to RNA-Seq data with a small (even with non-replicated) number of replicates. The validity of the proposed method is provided by applying it to various real and simulated datasets and comparing the results to those obtained from other competing methods.

Keywords: NGS, RNA-Seq, Exome-Seq, Statistical analysis, Small sample size

생물정보학 협동과정 주최