서울대학교 생물정보학 협동과정 주최로 세미나를 아래와 같이 열고자 하오니 많은 참여 바랍니다.

세미나는 Zoom을 통한 온라인 강의로 예정되어 있으며 강의에 참여하고자 하시는 분께서는 아래의 링크로 참여 부탁드리겠습니다.

일시: 2021년 11월 25일 목 요일 오전 11시

연사: 박웅양 연사님 (성균관대학교)

Zoom link:　https://snu-ac-kr.zoom.us/j/81203573636

Title:　Understanding tumor immune microenvironment of colorectal cancer

ABSTRACT :

Colorectal cancer (CRC) is a major cancer type with high mortality. Immune checkpoint inhibitor (ICI) therapy is approved for the treatment of CRC with high levels of microsatellite instability (MSI- H) with high tumor mutation burden and heavy infiltration of immune cell. However, the response rate of ICI in CRC with MSI-H has been reported to 50% in many clinical trials. Single cell genome analysis technique provides information on the proportion of major cell types and their gene expression profile. In particular, rare cell types or epigenetic regulation related to CRC can be investigated at single cell level. In this study, we analyzed immune and stromal cells in CRC at single cell gene expression level to understand the intercellular interactions related to immune response.