제목	2021년 3월 18일 생물정보학 세미나
작성자	관리자	작성일	2021-03-10
서울대학교 생물정보학 협동과정 주최로 세미나를 아래와 같이 열고자 하오니 많은 참여 바랍니다. 세미나는 Zoom을 통한 온라인 강의로 예정되어 있으며 강의에 참여하고자 하시는 분께서는 아래의 링크로 참여 부탁드리겠습니다.　 일시: 2021년 3월 18일　목요일 오전 11시 연사: 김윤근 연사님　(엠디헬스케어) Zoom link:　https://snu-ac-kr.zoom.us/j/81651508471 Title: Microbiome in Future Medicine Abstract Coelomate animals have coevolved with a diverse range of symbiotic microbes, collectively known as the environmental microbiota. Microbiota is involved in the regulation of multiple host immune and metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes. Host and gut microbes coproduce a large array of materials during the metabolism of food, many of which play critical roles in shuttling information between host cells and the host’s microbes. Extracellular vesicles (EVs) were found in 1960 through Electron Microscope (EM) when EVs in multivesicular bodies were observed in reticulocytes and released into the extracellular space. It was found that microbes also secrete EVs in 1960s using EM. Now, it is known that both prokaryotic and eukaryotic cells release EVs as means of intercellular communication, influencing neighboring and distant cells. Bacterial EVs are spherical bi-layered phospholipids ranging in size from 20-200 nm in diameter, called by nanovesicles, that are produced from both gram-negative and gram-positive bacteria during their proliferation and death. While commensal bacteria can not penetrate mucosal barrier, their secreting EVs can penetrate through the mucosal barriers, enter the systemic circulation, and then distribute to target organs and intracellular organelle. So, microbial EVs can be used as biomarkers. In this prestation, I will talk about microbial EVs in their role as a medicine.