서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 특별 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2015년 5월 14일 목요일 오전 11시

연사: 김 창 훈 소장님 (Macrogen 게놈 연구소)

장소: 서울대학교 25-1동 103호

TITLE

Large genome de novo assembly

ABSTRACT

De novo assembly of a large genome, from NGS data, is a challenging task. As new technologies emerge, there has been many improvements on de novo assembly algorithms and shotgun genome sequencing strategies. In this seminar, general issues regarding de novo assembly of NGS data will be discussed, especially focusing on the recent development of PacBio long read assembly combined with optical mapping data.

PUBLICATION

1.Lie, W., M. Onda, C. Kim, L. Xiang, J.E. Weldon, B. Lee and I. Pastan. 2012. A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity. PEDS. 25:1

2.Park, H., K.K. Kim, C. Kim, J.-M. Shin, K.T. No. 2013. Descriptor-Based Profile Analysis of Kinase Inhibitors to Predict Inhibitory Activity and to Grasp Kinase Selectivity. Bulletin of the Korean Chemical Society 34 (9), 2680-2684.

3. Choi, D.H., J.-Y. Ryu, K.-K. Kwon, J.-H. Lee, C. Kim, C. M. Lee, J. H. Noh. 2013. Draft genome sequence of Rubidibacter lacunae strain KORDI 51-2T, a cyanobacterium isolated from seawater of Chuuk lagoon. Stand. Genomics Sci. 9:197-204

4. Kim, J.-G., S.K. Park, H.-S. Park, S.-J. Kwon, S.-H. Kim, D.-J. Lee, S.-H. Sohn, B.M. Lee, S.-C. Bae, I.-P. Ahn, C. Kim, J.H. Baek. 2013. Genome Sequence Analysis of Chrysanthemum White Rust pathogen Puccinia horiana and Sterol 14-demethylase as Drug Target.

5. Park,Y.J., J.H. Baek, S. Lee, C. Kim, H. Rhee, H. Kim, J.-.S Seo, H.-R. Park, D.-E. Yoon, J.-Y. Nam, H.-I. Kim, J.-G. Kim, H. Yoon, H.-W. Kang, J.-Y. Cho, E.-S. Song, G.-H. Sung, Y.-B. Yoo, C.-S. Lee, B.-M. Lee, W.-S. Kong. 2014. Whole Genome and Global Gene Expression Analyses of the Model Mushroom Flammulina velutipes Reveal a High Capacity for Lignocellulose Degradation. PLOS ONE. 9:e93560.