서울대학교 생물정보연구소와 생물정보학 협동과정 공동 주최로 특별 세미나를 아래와 같이 열고자 하오니, 많은 참여 바랍니다.

일시: 2015년 5월 7일 목요일 오전 11시

연사: 원 성 호 교수님 (서울대학교 보건대학원 보건학과)

장소: 서울대학교 25-1동 103호

TITLE

Genetic association analysis with sequencing data

ABSTRACT

Common disease rare varaints hypothesis(CDRV) assumes that the risk for a common disease is influenced by multiple rare variants with strong genetic effects, implying that only a few cases share the same causal variants. With the arrival of high-throughput sequencing data, rare variants are the focus of genetic association

studies. However, because single variant analysis has insufficient power to address analysis questions posed by the CDRV hypothesis, various analytical approaches have been suggested for the characterization of rare variants. One main approach is to

collapse the genetic information of rare variants in a region and to construct an overall test statistic. Here, we review various approaches for rare variant association analyses.

서울대학교 생물정보연구소

생물정보학 협동과정 공동주최